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Managing patients with type1 diabetes when fasting Ramadan is very challenging. Insulin pump offers the advantage of flexibility and precision to administering insulin and has been proven to reduce severe hypoglycemia compared to multi-dose injection (MDI). However, there are extremely limited studies on the difference between insulin pump compared to MDI on the incidence of hypoglycemia and other acute complications during fasting Ramadan
The investigators hypothesized that insulin pump would be associated with less hypoglycemic events during fasting Ramadan compared to MDI without deterioration in glycemic control. Results of this study are descriptive but will fill a current gap in knowledge and may contribute to development of future guidelines for the management of type1DM during Ramadan.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Insulin pump | |||
| MDI |
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| Measure | Description | Time Frame |
|---|---|---|
| Incidence of hypoglycemia | Rates of hypoglycemia during fasting ramadan in insulin pump users and MDI users [Hypoglycemia defined as blood glucose level ≤ 70 mg/dl ( 3.9 mmol/l)] | 5 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Number of fasting days lost | To estimate the number of days they needed to brake their fast due to acute complications (hypoglycemia, severe hyperglycemia, or DKA). | 5 weeks |
| Glycemic control | To assess the glycemic control in the two groups using HbA1c and Fructosamine assays. |
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Inclusion Criteria:
Exclusion Criteria:
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The target population of our study is all patients with type1DM treated at three National Guard institutiuons in three different cities of Saudi Arabia (Riyadh, Alahsa, Dammam) with either insulin pump or MDI
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Guards Hospital | Dammam | 31412 | Saudi Arabia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30294552 | Derived | Alamoudi R, Alsubaiee M, Alqarni A, Aljaser S, Saleh Y, Salam A, Eledrisi M. Attitudes and habits of patients with type 1 diabetes during fasting Ramadan. J Clin Transl Endocrinol. 2018 Sep 6;14:1-4. doi: 10.1016/j.jcte.2018.09.001. eCollection 2018 Dec. |
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| ID | Term |
|---|---|
| D003922 | Diabetes Mellitus, Type 1 |
| D005215 | Fasting |
| D003920 | Diabetes Mellitus |
| D007333 | Insulin Resistance |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| Two (2) months |
| overnight hypoglycemia | To estimate the rates of overnight hyperglycemia in both groups. | 5 weeks |
| Rate of acute complications | To estimate presence of severe hyperglycemia and /or DKA episodes in both groups | 5 weeks |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D005247 | Feeding Behavior |
| D001519 | Behavior |
| D006946 | Hyperinsulinism |