To establish the optimal imaging technique of PET/MR using multiple radioactive tracers for prostate cancer
- Recruiting 30 patients with prostate cancer ahead to radical prostatectomy
- PET/MR using 18F-choline with dedicated prostate MRI in all patients
- PET/MR using 18fluoride(F)-fluorodeoxyglucose(FDG)in all patients after 2-7 days
- PET/CT using 18F-FDG in all patient immediate after 18F-FDG PET/MR
- outcome assessment: comparison of scan time, image quality, tumor detection rate, standardized uptake values of lesions
- establishing optimal imaging technique for prostate PET/MR
To establish the imaging biomarker using PET/MR for clinical assessment of prostate cancer
- comparison of findings on PET/MR, MRI and PET/CT with pathological mapping after radical prostatectomy
- outcome assessment: accuracy of PET/MR for localization and staging of prostate cancer compared with MRI only and PET/CT only
To establish the imaging biomarker using PET/MR for early detection of recurrent prostate cancer
- Recruiting 15 patients with recurrent prostate cancer treated by surgery, hormone, or radiation therapy
- Recruiting 15 patients with treated prostate cancer without recurrence
- PET/MR using 18F-choline with dedicated prostate MRI in all patients
- PET/MR using 18F-FDG in all patients after 2-7 days
- PET/CT using 18F-FDG in all patient immediate after 18F-FDG PET/MR
- comparison of findings on PET/MR, MRI, and PET/CT with clinical data in two patient groups with or without recurrent prostate cancer
- outcome assessment: accuracy of PET/MR for early detection and localization of recurrent prostate cancer compared with MRI only and PET/CT only