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| Name | Class |
|---|---|
| Moi University | OTHER |
| Academic Model Providing Access to Healthcare (AMPATH) | OTHER |
| Regenstrief Institute, Inc. | OTHER |
| Innovative Support to Emergencies, Diseases and Disasters (InSTEDD) |
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The overall research objective is to evaluate the impact of implementing a reminder system for medical providers to improve TB case-finding and isoniazid preventative therapy (IPT) for adults living with HIV in western Kenya
The purpose of this study is to evaluate the impact of implementing a clinical decision support reminder system for medical providers (i.e., nurses, clinical officers, medical officers, consultants) to improve tuberculosis case-finding and the use of isoniazid preventative therapy for adults living with HIV in western Kenya.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| TB reminders | Experimental | Receive existing reminders plus new patient-specific reminders about TB screening, prevention, and treatment |
|
| No TB reminders | No Intervention | Only receive existing reminders; no TB reminders |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| TB reminders | Behavioral | The intervention to be studied involves providing clinic-based medical care providers (e.g., nurses, clinical officers, medical officers, consultants) with patient-specific clinical reminders regarding TB that are generated from a patient's electronic medical record and based on accepted clinical algorithms for TB screening and treatment. |
| Measure | Description | Time Frame |
|---|---|---|
| Prescription of Isoniazid | Provider prescribes INH within 3 months of patient's initial encounter. | within 3 months of initial encounter |
| Measure | Description | Time Frame |
|---|---|---|
| Time to isoniazid prophylactic therapy (IPT) initiation | The time in weeks from a patient's initial encounter to the week the patient picks up the initial batch of INH from the pharmacy. | within 3 months of initial encounter |
| Measure | Description | Time Frame |
|---|---|---|
| Initiation of isoniazid prophylactic therapy (IPT) | IPT will be considered "initiated" when a patient picks up the initial batch of the prescribed medications within 3 months of the initial encounter. | within 3 months of initial encounter |
| Isoniazid prophylactic therapy (IPT) completion |
Clusters:
Inclusion Criteria
Exclusion Criteria -
Patients:
Inclusion Criteria
Exclusion Criteria
- history of TB or IPT
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| Name | Affiliation | Role |
|---|---|---|
| Lameck O Diero, MBChB, MMed | Moi University College of Health Sciences | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| AMPATH | Eldoret | Kenya |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25885266 | Derived | Green EP, Catalani C, Diero L, Carter EJ, Gardner A, Ndwiga C, Keny A, Owiti P, Israelski D, Biondich P. Do clinical decision-support reminders for medical providers improve isoniazid preventative therapy prescription rates among HIV-positive adults? Study protocol for a randomized controlled trial. Trials. 2015 Apr 9;16:141. doi: 10.1186/s13063-015-0558-8. |
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| ID | Term |
|---|---|
| D014376 | Tuberculosis |
| ID | Term |
|---|---|
| D009164 | Mycobacterium Infections |
| D000193 | Actinomycetales Infections |
| D016908 | Gram-Positive Bacterial Infections |
| D001424 | Bacterial Infections |
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| UNKNOWN |
| Kijani Consulting | UNKNOWN |
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|
Patient completes 9-month course of IPT |
| 9 months after treatment initiation |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |