Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of the study is to assess among others environmental and hygiene-related risk factors for microscopic colitis (MC), a common diarrheal disease.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Microscopic Colitis | Group consists of subjects diagnosed with either collagenous of lymphocytic colitis between January 1, 2000 and December 31, 2012 |
| |
| Healthy Controls | Control group consists of subjects with no history of microscopic colitis. Group is age and sex matched with the case-group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Whole saliva sample | Other | Both case and control group will be approached to consider to give permission to sample saliva. This is not obligatory. Collected samples will be stored for future DNA research. |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of environmental and hygiene-related risk factors for microscopic colitis | Information about environmental and hygiene-related risk factors is obtained by a questionnaire, sent to subjects diagnosed with MC between 2000 and 2012 | Retrospective, between 2000 and 2012 |
| Measure | Description | Time Frame |
|---|---|---|
| The difference between the CC and LC subpopulation regarding environmental, hygiene-related, and generally known risk factors | As generally known risk factors are considered: age, gender, medication, comorbidities and smoking. Information about risk factors is obtained by a questionnaire, sent to subjects diagnosed with MC between 2000 and 2012. | Retrospective between 2000 and 2012 |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
The case group will be selected by a retropective search in the pathology registry. Subjects have to be diagnosed between January 1, 2000 and December 31, 2012; have to be older than 18 years of age and have to be living in the province of Limburg, the Netherlands.
Healthy controls are selected via the municipal personal records databases in the same region.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Marieke J Pierik, MD, PhD | Maastricht UMC | Principal Investigator |
| Daisy MAE Jonkers, PhD | Maastricht University | Principal Investigator |
| Ad AM Masclee, Prof. | Maastricht UMC | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Maastricht UMC | Maastricht | Limburg | Netherlands |
Not provided
| ID | Term |
|---|---|
| D046728 | Colitis, Microscopic |
| D046729 | Colitis, Collagenous |
| D046730 | Colitis, Lymphocytic |
| ID | Term |
|---|---|
| D003092 | Colitis |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
saliva samples
| D003108 |
| Colonic Diseases |
| D007410 | Intestinal Diseases |