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| ID | Type | Description | Link |
|---|---|---|---|
| NCI-2013-01626 | Registry Identifier | CTRP (Clinical Trial Reporting Program) |
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| Name | Class |
|---|---|
| Siemens Healthcare QT | INDUSTRY |
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This pilot clinical trial studies perfusion computed tomography (CT) in predicting response to treatment in patients with advanced kidney cancer. Comparing results of diagnostic procedures done before, during, and after targeted therapy may help doctors predict a patient's response to treatment and help plan the best treatment.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| perfusion computed tomography | Device | Undergo perfusion CT |
|
| Measure | Description | Time Frame |
|---|---|---|
| Characterization of the relationship between Change in blood flow measured through perfusion CT techniques and Change in tumor size measured through non-investigational CT | 12 weeks (+/- 5 days) after start of standard systemic targeted therapy medication |
| Measure | Description | Time Frame |
|---|---|---|
| Characterization of the relationship between change in perfusion CT measurements (eg. Mean transit time) and change in tumor size measured by non-investigational CT | 12 weeks (+/- 5 days) after start of standard systemic targeted therapy medication | |
| Relationship between change in blood flow and tumor response measured on ordinal scale |
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Inclusion Criteria:
Exclusion Criteria:
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Subjects with metastatic renal cell carcinoma prescribed a systemic targeted therapy medication
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| Name | Affiliation | Role |
|---|---|---|
| Aya Kamaya | Stanford University Hospitals and Clinics | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Stanford University Cancer Institute | Stanford | California | 94305 | United States |
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| ID | Term |
|---|---|
| D002292 | Carcinoma, Renal Cell |
| ID | Term |
|---|---|
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
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| ID | Term |
|---|---|
| D014057 | Tomography, X-Ray Computed |
| ID | Term |
|---|---|
| D007090 | Image Interpretation, Computer-Assisted |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| 12 weeks (+/- 5 days) after start of standard systemic targeted therapy medication |
| Relationship between change in blood flow at Day 8 and change in tumor size measured on continuous scale at Week 12 and tumor response measured on ordinal scale at Week 12 | 12 weeks (+/- 5 days) after start of standard systemic targeted therapy medication |
| Relationship between change in blood flow at Day 8 and at Week 12 and progression-free survival | 12 weeks after start of standard systemic targeted therapy medication |
| Relationship between change in blood flow at Day 8 and at Week 12 and time to nadir of tumor size | 12 weeks after start of standard systemic targeted therapy medication |
| D009369 | Neoplasms |
| D007680 | Kidney Neoplasms |
| D014571 | Urologic Neoplasms |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052801 | Male Urogenital Diseases |
| D011856 | Radiographic Image Enhancement |
| D007089 | Image Enhancement |
| D010781 | Photography |
| D011859 | Radiography |
| D014056 | Tomography, X-Ray |
| D014054 | Tomography |