To study the effects of Erigeron Injection on human serum VEGF, MMP-9 and EPC levels after acute cerebral infarction,test is made by random double-blind controlled.patients with acute cerebral infarction were divided randomly into erigeron injection+aspirin group,aspirin group,and health people. The main indexes are the serum level of VEGF, MMP-9 and EPC.The review is made by the reference to NIHSS and so on. So, Erigeron Injection have the function of promoting angiogenesis in multiple targets through this test.

OBJECTIVE:

To study the effects of Erigeron Injection on human serum VEGF, MMP-9 and EPC levels after acute cerebral infarction.

METHOD:

40 patients with acute cerebral infarction(in accordance with the inclusion criteria) were divided randomly into erigeron injection+aspirin group,aspirin group,and 20 health people. Erigeron injection+aspirin group and aspirin group drew peripheral blood on the prior treatment,the posttreatment 1th, 3th and 7th day,and tested the level of VEGF, MMP-9 and EPC.Tested the health people one time.

Inclusion Criteria:

• patients aged no younger than 18yrs
• attack within 72 hours
• NIHSS score in the 2-25 points
• Ischemic Stroke occurred for the first time, or with a history of stroke disease but without sequelae
• Signed the informed consents

Exclusion Criteria:

• patients aged younger than 18yrs
• Patients with tumor, coronary heart disease, valvular heart disease, psoriasis, rheumatism, hematologic diseases, infertility, varieties of acute inflammation
• Patients with severe cognitive impairment
• Refused to cooperate or been unable to cooperation for neurological disorders
• Cerebral hemorrhage or hemorrhagic cerebral infarction
• Unstable vital signs dued to massive cerebral infarction
• Patients with serious heart, liver and renal insufficiency