This study is being done to learn more about how different surgery procedures bring back the quality of life.After removing the small intestine at least 20cm in patients with pancreatic cancer, Some patients develop problems because they are disorder their digestive system, such as cramping, heartburn,vomiting.

Inclusion Criteria:

• Patient 30 years of age or older
• Pathologically confirmed pancreatic cancer (biopsy may be performed at our institution)
• No evidence of metastases(a)
• decide performe Roux-en-Y(b)
• single Roux-en-Y reconstruction is technically feasible(c)
• Patients will be registered and consent obtained, if the surgeon believes there is no evidence of metastases. If metastatic disease is identified at the time of operation, the patient will not be randomized.
• Patients will be conditionally enrolled, and consent obtained, if the surgeon believes the patient may need a sngle Roux-en-Y at the time of operation. If a sngle Roux-en-Y is not performed, the patient will not be randomized.
• the surgeon feels that the single Roux-en-Y is not technically feasible at the time of operation,the patients will be excluded. This may be due to prior abdominal surgery, anatomic variants, or anything else at the surgeon's discretion.

Exclusion Criteria:

• Not expected to be able to provide follow-up over 2 years (due to geographic or other limitations)

Patients with pancreatic cancer