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| ID | Type | Description | Link |
|---|---|---|---|
| ERN_09-586 | Registry Identifier | University of Birmingham |
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The primary aim of this study was to determine the effects of an acute bout of high intensity exercise on the brains response to viewing pictures of food using functional magnetic resonance imaging (fMRI).
It is clear that intense exercise impacts on peripheral appetite regulation, however very little is known about the impact of high-intensity exercise on central appetite regulation. This study aimed to investigate the effects of high-intensity exercise on both central and peripheral responses to images of food. Functional magnetic resonance techniques were used to assess the brains response to images of high and low calorie foods, following a short bout of high-intensity exercise. Appetite hormone concentrations were also measured. It was hypothesized that, due to the known effects of high-intensity exercise on appetite regulatory hormones and subjective appetite ratings, the activation of reward-related brain regions to visual food cues would be modulated following intense physical activity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Exercise | Experimental | 60 minutes of high intensity treadmill running |
|
| Rest | Experimental | 60 minutes of seated rest (control trial) |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise | Other |
| ||
| Rest |
| Measure | Description | Time Frame |
|---|---|---|
| Neural responses following exercise and rest | Volunteers completed an fMRI assessment following 60 minutes of intense exercise and 60 minutes of rest on two separate occasions. | Ten minutes post-exercise/rest |
| Measure | Description | Time Frame |
|---|---|---|
| Appetite hormones | Blood samples were taken using a cannula system for both trials. Concentrations of appetite regulating hormones were measured from plasma. | Blood samples taken at baseline, following exercise/rest, prior to the fMRI assessment and immediately following the fMRI assessment |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Andrew Blannin, PhD | University of Birmingham | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Birmingham University Imaging Centre | Birmingham | Midlands | B15 2TT | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24305681 | Derived | Crabtree DR, Chambers ES, Hardwick RM, Blannin AK. The effects of high-intensity exercise on neural responses to images of food. Am J Clin Nutr. 2014 Feb;99(2):258-67. doi: 10.3945/ajcn.113.071381. Epub 2013 Dec 4. |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| C092779 | RE1-silencing transcription factor |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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