Effects of Aspirin and Low Molecular Weight Heparin in IVF Outcome.

Effects of Low Dose Aspirin and Low Molecular Weight Heparin Cotreatment, Alone and/or in Combination on Implantation and Clinical Pregnancy Rates in Repeated Implantation Failures in IVF Cycle.

The purpose of the study is to determine whether low-dose aspirin and low molecular weight heparin improve the implantation and pregnancy rates in patients with repeated implantation failures in IVF cycle.

The investigators hypothesize that cotreatment of low dose aspirin & low molecular weight heparin may improve implantation & clinical pregnancy rates.

Inclusion Criteria:

• Aged between 19 to 35 years;
• Basal follicle-stimulating hormone (FSH) levels of ≤8 IU/l
• Body mass index (BMI) between 19 kg/m2 and 25 kg/m2
• Presence of both ovaries; ≥2 previous IVF failures
• Good quality embryos for transfer
• Endometrial thickness between 10 mm and 14 mm

Exclusion Criteria:

• Polycystic ovary syndrome
• Endometriosis