Screening for Endometrial Abnormalities in Overweight and Obese Women

Screening for Endometrial Abnormalities in Overweight and Obese Women

The purpose of this study is to develop an endometrial biopsy screening program for endometrial cancer and its precursor lesions in overweight and obese women.

There is a BMI threshold at and above which optimal screening parameters exist for identifying endometrial cancer and its precursor lesions in overweight and/or obese women. Prevention, diagnosis and treatment of endometrial cancer and its precursor lesions in overweight and/or obese women offers substantial health benefits.

INCLUSION CRITERIA:

• Have BMI ≥25.
• Be patients of the St. Luke's and Roosevelt Gynecology Clinics and Faculty Practices OR be receiving bariatric surgery.
• Complete a full medical history, a detailed menstrual and/or postmenopausal bleeding history, and endometrial biopsy.
• Have a negative pregnancy test, if of childbearing age.
• Be at least 18 years of age.
• Have signed a written Informed Consent Document.
• Be willing and able to comply with the study requirements.

EXCLUSION CRITERIA:

• Have a BMI <25.
• Have a prior hysterectomy.
• Be pregnant or have a positive pregnancy test
• Have untreated vaginal, cervical, or adnexal infection.
• Recent treatment of STD