Negative Pressure Drainage System Split-thickness Skin Graft Recipient Sites

The Use of "Negative Pressure Drainage System" for Caring Split-thickness Skin Graft Recipient Sites

To compare the efficacy and safety of negative pressure drainage system with controls (indirect saline soaks) in the coverage of recipient site wounds of split-thickness skin graft.

Randomized, comparator-controlled trial in patients underwent split-thickness skin graft conducted in Taipei Veterans General Hospital between Aug. 2012 and Dec. 2013. (No.) patients age 21 to 60 years were randomly assigned in the intervention group (n= ) of negative pressure drainage system or to a control group (n= ) of traditional method. Patients who had immunologic disease, end-stage renal disease, coagulopathy, or history of radiation were excluded. The conditions of graft take and pain and discomfort were compared every day during the first 7 days after operation and 2 weeks and 3 months follow up.

Inclusion Criteria:

• Aged 21 to 60 years
• The wounds located on limbs or trunk
• The area of wounds is ranged 50 to 250cm2.

Exclusion Criteria:

• immunodeficiency disease
• end stage renal disease
• coagulopathy
• history of radiation to the recipient site
• allergy to the dressing
• major medical problems