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| ID | Type | Description | Link |
|---|---|---|---|
| EA4/073/10 | Other Identifier | Charité Ethics Committee |
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| Name | Class |
|---|---|
| Center for Stroke Research Berlin | OTHER |
| Cardiology and Angiology, Elisabeth Hospital, Essen, Germany | UNKNOWN |
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The purpose of this prospective single-center trial is to compare the safety and diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging and transesophageal echocardiography in patients with acute ischemic stroke.
Primary safety objective: Contrast medium-enhanced cardiac magnetic resonance imaging is safe in patients with acute ischemic stroke. Primary outcome: The diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging is comparable to transesophageal echocardiography in patients with acute ischemic stroke.
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| Measure | Description | Time Frame |
|---|---|---|
| Sensitivity and specificity of contrast medium-enhanced cardiac magnetic resonance imaging to detect echocardiography-proven cardiac sources of embolism in patients with acute ischemic stroke. | < 1 week after ischemic stroke |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of unrecognised myocardial infarction detected by late gadolinium-enhanced cardiac MRI in patients with acute ischemic stroke. | < 1 week after ischemic stroke |
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Inclusion Criteria:
Exclusion Criteria:
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Overall, 103 patients with acute ischemic stroke detected by brain magnetic resonance imaging will be enrolled.
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| Name | Affiliation | Role |
|---|---|---|
| Prof. Matthias Endres, MD | Center for Stroke Research Berlin | Study Chair |
| Karl Georg Haeusler, MD | Center for Stroke Research Berlin | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Charité, Universitätsmedizin Berlin, Campus Benjamin Franklin | Berlin | 12203 | Germany | |||
| Elisabeth Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28411261 | Derived | Haeusler KG, Wollboldt C, Bentheim LZ, Herm J, Jager S, Kunze C, Eberle HC, Deluigi CC, Bruder O, Malsch C, Heuschmann PU, Endres M, Audebert HJ, Morguet AJ, Jensen C, Fiebach JB. Feasibility and Diagnostic Value of Cardiovascular Magnetic Resonance Imaging After Acute Ischemic Stroke of Undetermined Origin. Stroke. 2017 May;48(5):1241-1247. doi: 10.1161/STROKEAHA.116.016227. Epub 2017 Apr 14. |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| Essen |
| Germany |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |