Healing of Punch Graft Wounds. Comparative Study Between MariGen and Oasis: a Non-inferiority Study

Healing of Punch Graft Wounds With Two Biologic Exracellular Matrices; a Non-inferiority Study

The objective is to determine, if healing of punch biopsy wounds treated with the fish skin derived MariGen Wound dressing is non-inferior to healing with wounds treated with pig intestines derived Oasis Sheet wound dressing. Secondary endpoints are: Incidence of erythema, Pain, Infection, Quantitative measurements of autoantibodies at baseline and 4 weeks after start of treatment

Inclusion Criteria:

• >18 yrs
• Healthy individual
• Signature of informed consent

Exclusion Criteria:

• Autoimmune disease
• Immunosuppressive treatment
• Use of addictive drugs
• Excessive use of alcohol
• Known fish allergy
• Known allergy to proteins with porcine origin
• Peripheral vascular disease
• Pregnant women
• Persons receiving anticoagulation therapy or systemic corticosteroids will be excluded.