Pulsed Dye Laser Treatment of Onychomycosis

Pulsed Dye Laser Treatment of Onychomycosis

The purpose of this research is to investigate the use of the Candela V-beam Pulsed Dye Laser for the treatment of onychomycosis, or nail fungus.

Hypothesis: Complete nail clearance will occur in approximately half of patients after 3 laser treatments.

10 patients will participate nationally. The investigators hope to enroll all 10 patients at Jefferson. Involvement in the study will last about 8-12 weeks for the subject. The entire study will take about 12 months to complete.

Inclusion Criteria:

• Ages 18-65 years old
• Diagnosis of onychomycosis based on positive fungal culture for dermatophyte and positive PAS from toenail clipping

Exclusion Criteria:

• HIV/immunosuppression
• Candidal toenail infection
• Prior PO antifungal therapy within last 6 months
• Personal history of psoriasis, lichen planus, or significant photosensitivity disorder
• Any serious generalized medical condition