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The purpose of BEHHS is first to assess the baseline sub-clinical disease in a population of Baptist Health Employees who have Metabolic Syndrome, a known contributor to cardiovascular disease. Second, the investigators wish to encourage a healthy lifestyle through personalized nutrition and fitness advice, delivered as part of a web based program, which will in turn lead to increases in heart healthy behaviors such as increased consumption of heart healthy foods, increased exercise initiation, and more positive attitudes about health. To assess this, the investigators plan to randomize 200 employees with Metabolic Syndrome to either the new web-based diet and lifestyle program, or to care-as-usual, which is the currently offered MyWellnessAdvantage and WebMD websites. The investigators hypothesize that the web-based group will show greater improvements in physical health (such as weight loss, cholesterol reduction, etc.) as well as increased consumption of heart healthy foods, exercise initiation, and quality of sleep as measured by surveys administered at the 4,8, and 12 month follow-up appointments.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| My Everyday Health Group | Experimental | Subjects in this group will be randomized to a web based diet and weight modification program (MyEveryday Health) and provided personal access codes. They will also continue to have access to the WebMD website provided as part of their employment with Baptist Health South Florida. |
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| WebMD Group | No Intervention | This group will continue to have access to a website that is available for use of all employees (WebMD) at Baptist Health South Florida. This is the care-as-usual arm. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| My Everyday Health | Behavioral | MyEveryday Health is a web-based nutritional and lifestyle management program. The program includes personalized diet and weight guidance, meal planners, shopping list generator, recipe finder, weight tracker and dining out and fast food guides. Based on specific algorithms, tips and suggestions on how to make changes in their diet and lifestyle will be give each time the subject logs in. The MyEverydayHealth website will also be available as an app for their smart phone to the participants. If they choose to use the app, daily reminders to log in and use their tools will be sent, along with motivating tool/tips/tricks to stay with the program. |
| Measure | Description | Time Frame |
|---|---|---|
| Reduction in BMI | 4 months, 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in waist circumference | 4 months, 12 months | |
| Change in Lipids | Examining any changes in advanced lipids such as HDL, LDL, triglycerides, particle size | 4 months, 12 months |
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Inclusion Criteria:
Employee of Baptist Health
Access to Internet
Has a smart phone (Android or Apple supported) with data plan
Has an email address
Diagnosis of three or more of the following:
Waist circumference >=40 inches in and male and >= 35 inches in a female
Fasting triglyceride level > 150 mg/dl*
HDL-C < 40 mg/dl in men or < 50 mg/dl in women*
BP > 130/85 mm Hg*
Fasting blood glucose > 110 mg/dl
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Khurram Nasir, MD, MPH | Baptist Health Medical Group | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| South Miami Heart Center Outpatient Services | Miami | Florida | 33143 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32193785 | Derived | Aziz M, Gannarapu S, Humayun C, Siddiqui U, Nasir K, Aneni EC. Association of particles of lipoprotein subclasses with arterial stiffness in a high-risk working population: the Baptist Employee Healthy Heart Study (BEHHS). Egypt Heart J. 2020 Mar 19;72(1):12. doi: 10.1186/s43044-020-00046-4. | |
| 27369488 | Derived |
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| ID | Term |
|---|---|
| D024821 | Metabolic Syndrome |
| D002318 | Cardiovascular Diseases |
| D050197 | Atherosclerosis |
| D009765 | Obesity |
| D015431 | Weight Loss |
| ID | Term |
|---|---|
| D007333 | Insulin Resistance |
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
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|
| Change in Blood Pressure | 4 months, 12 months |
| Change in Glucose Regulation | Change in fasting blood glucose(FBG) and HbA1C | 4 months, 12 months |
| Lifestyle Change | Changes in reported physical activity, diet, and behavioral scores based on self report by survey | 4 months, 12 months |
| Change in Sub-Clinical Disease | Change in measures of sub-clinical cardiovascular disease; Endothelial function, Carotid intima-medial thickness, coronary artery calcium | 12 months |
| Post JM, Ali SS, Roberson LL, Aneni EC, Shaharyar S, Younus A, Jamal O, Ahmad R, Aziz MA, Malik R, Spatz ES, Feldman T, Fialkow J, Veledar E, Cury RC, Agatston AS, Nasir K. Rationale and design of the Baptist Employee Healthy Heart Study: a randomized trial assessing the efficacy of the addition of an interactive, personalized, web-based, lifestyle intervention tool to an existing health information web platform in a high-risk employee population. Trials. 2016 Jul 1;17(1):308. doi: 10.1186/s13063-016-1424-z. |
| D009750 |
| Nutritional and Metabolic Diseases |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001836 | Body Weight Changes |