The purpose of this study is to assess the efficacy of Askina® Calgitrol® Paste in reducing local infection in subjects treated for mildly infected Diabetic Foot Ulcers (DFU) with Askina® Calgitrol® Paste.

Inclusion Criteria:

• Subject older than 18 years old

• Provision of written consent by the subject themselves

• Subjects with a Texas stage I-B wound below the malleolus: superficial and infected (Wagner-Armstrong classification system).

• Subjects with a mildly infected wound according to the Infectious Diseases Society of America (IDSA).

• Size of wound >2 cm2.

• Absence of ischaemia of the lower limb as assessed by :

  1. Transcutaneous oxygen pressure (TcPO2) > 30 mmHg.
  2. Toe pressure > 50 mmHg.
  3. Ankle pressure > 70 mmHg.

• Capable of following Study instructions.

• Compliant with treatment and in particular with off-loading regime.

• Stable management of their diabetes as defined by an HbA1C (%) of 12%

Exclusion Criteria:

• Subjects who are <18 years old.
• Subjects with a documented sensitivity to alginates or silver.
• Subjects taking a medication or using a device comprising silver.
• Subjects already taking antibiotics before enrolment
• Subjects undergoing dialysis.
• Subjects using therapy known to be immune-compromising such as systemic anti-neoplastic drugs and/or systemic cortico-steriods.
• Pregnancy
• Breast-feeding
• Currently participating in another clinical trial, or who have participated in another clinical trial in the last 6 weeks or who have previously taken part in this study