STUDY ON THE EFFECTS OF PERIODONTAL TREATMENT ALONG WITH THE USE OF ANTIBIOTICS OVER HIGH SENSITIVE C-REACTIVE PROTEIN. RANDOMIZED CONTROLLED CLINICAL TRIAL.

STUDY ON THE EFFECTS OF PERIODONTAL TREATMENT ALONG WITH THE USE OF ANTIBIOTICS OVER HIGH SENSITIVE C-REACTIVE PROTEIN. RANDOMIZED CONTROLLED CLINICAL TRIAL.

Human periodontitis is a group of highly prevalent oral inflammatory diseases and infections with relatively easy treatment and preventive features. The present study is aimed to determine if treating human individuals with chronic periodontitis, along with the use of antibiotics, reduces cardiovascular risk marker (HsPCR) and also intends to identify if severity of periodontitis could be associated with a raise of systemic inflammatory biomarkers on baseline.

Inclusion Criteria:

• must be of legal age (≥ 18 years old)
• voluntary participation and signed information consent
• confirmed systemically healthy individual
• at least 15 teeth present in mouth

Exclusion Criteria

• pregnant women
• smokers
• antibiotic consumption 6 months before inclusion
• HIV positive or AIDS
• Allergic reactions to macrolides and specifically to azithromycin
• Periodontal treatment 6 months before inclusion