Anti-inflammatory Effect of Aerobic Exercise in Individual With Increased Cardiovascular Risk
Anti-inflammatory Effect of Aerobic Exercise in Individual With Increased Cardiovascular Risk
Aerobic physical activity attenuates systemic inflammatory activity in individuals with cardiovascular risk.
Background: Observational studies suggest that exercise has anti-inflammatory effect, however this idea has not been definitively confirmed by randomized clinical trials.
Objective: To test the hypothesis that aerobic exercise attenuates systemic inflammatory activity in individuals with cardiovascular risk.
Methods: Randomized controlled trial, which included 68 sedentary individuals, with at least two risk factors for coronary heart disease or established cardiovascular disease. The volunteers were randomized to 3 months of supervised aerobic training or just advice when healthy lifestyles. C-reactive protein (CRP) was measured by the method of high sensitivity before and after 3 months of intervention.
Inclusion Criteria:
- Individuals with are between 40 to 70 years, no regular exercise, and at least two risk factor for cardiovascular disease (diabetes, hypertension, dyslipidemia, smoking) or documented cardiovascular disease.
Exclusion Criteria:
- Incapacity to exercise.