Primary objective: Evaluate the prevalence of personality disorders in patients starting treatment for hepatitis C in the prison and determine their influence on the evolution of the disease.

Secondary objectives:

• Describe the management of patients with personality disorders on treatment for hepatitis C in the prison.
• Describe the characteristics of patients who discontinue the treatment and the reasons for stratifying by the presence of personality disorders.

Inclusion Criteria:

• Patients 18 years of age.
• Patients with expected prison stay beyond the duration of follow-up period of the study.
• Patients with chronic HCV infection and detectable viral load to initiate treatment with standard therapy.
• Patients their written informed consent to participate in the study.

Exclusion Criteria:

• Patients previously treated with Interferon (IFN) and Ribavirin (RBV).
• Patients can not read or understand a written questionnaire at the discretion of the investigator.

The study population will consist of patients with chronic hepatitis C mono-or co-infected with HIV.