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| ID | Type | Description | Link |
|---|---|---|---|
| 2013-A00943-42 | Other Identifier | ANSM |
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| Name | Class |
|---|---|
| Centre Scientifique de Monaco | OTHER |
| Pfizer | INDUSTRY |
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Background :
Community-acquired pneumonia (CAP) is a threat in industrialized countries. It represents the 6th cause of death. CAP also frequently associates with other disorders responsible for admission and death. Among bacteria responsible for CAP, Streptococcus pneumonia is a major pathogen that is commonly involved and frequently leads to severe infection and admission. Categories at risk for this pathogen have been determined, and can be proposed anti-pneumococcal vaccination (APV) that efficiently and safely protects from this microorganism.
In the context of US health services, monocenter pilot experiences have reported improvement of pneumococcal prophylaxis implementing vaccination procedure at ED. A study that set in New Mexico (2003) reported a significant increase in APV (from 18% to 84%) when patients at risk were proposed vaccination at ED. To obtain these results, medical students were specifically trained and dedicated to screen and vaccinate against St. pneumoniae. Another single center trial (Tennessee, 2007) for APV at ED obtained an improvement (from 38.8 to 45.4%) when physicians were alerted for pneumococcal risk by the software they usually utilized at bedside. However these experiences remain sparse as additional dedicated resources are required or patients and attending ED physicians can be reluctant to proceed to vaccination at ED.
Mobile phone and derived communication modalities are current vectors to deliver information in several fields including education and medicine. Initially used in developing countries, short-message services (SMS) have improved behaviour of patients in various medical areas. In France, the investigators have observed that most patients above 50 years of age admitted after ED visit are equipped with mobile phone and can receive alerts by SMS.
These observations prompt us to propose a multifaceted procedure to improve APV after ED visit in at-risk patients, combining structured oral interview, written information and SMS as reminders.
Purpose : The investigators hypothesized that
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Multifaceted |
| ||
| Control |
|
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| Measure | Description | Time Frame |
|---|---|---|
| Impact of a multifaceted procedure at ED visit on anti-pneumococcal vaccination. (APV) at 6-month. Evaluation criteria : Δ percentage (%) of APV vaccination at 6-month | 6 month |
| Measure | Description | Time Frame |
|---|---|---|
| On Flu vaccination at 6-month Δ percentage (%) | number of patients receiving vaccination against flu at 6-month. This issue will be collected by phone (patient, relative or general practioner). This will be a declarative data | 6 month |
| On episodes of respiratory tract infections requiring antibiotics or admission at 6-month Δ (absolute number of events) |
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Inclusion Criteria:
Exclusion Criteria:
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patient aged 65 years or over who is not vaccinated against pneumoccocus virus during consultation with medical emergencies
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| Name | Affiliation | Role |
|---|---|---|
| Yann-Erick CLAESSENS, MD-PHD | Centre Hospitalier Princesse Grace | Study Director |
| Xavier DUVAL, MD-PHD | Groupe Hospitalier Bichat Claude-Bernard | Study Director |
| José LABARERE, MD | University Hospital, Grenoble | Study Director |
| Jocelyn RAUDE, PHD | Ecole des Hautes Etudes en Santé Publique | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier Universitaire de Clermont-Ferrand | Clermont-Ferrand | 63003 | France | |||
| Centre Hospitalier Paul Ardier |
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number of patients who experienced respiratiory tract infection requiring antibiotics or admission. This issue will be collected by phone at 6-month (patient, relative or general practioner). This will be a declarative data |
| 6 month |
| On death at 6- and 12-month (absolute number of events) | 6 month |
| On death related to infection at 6- and 12-month (absolute number of events) | 6 month |
| Psychosocial evaluation of patients and acceptance / refusal of vaccination | The patient will fil a Psychosocial evaluation questionnaire during the ED visit. To achieve this issue, we will use the socio-economic indicators mobilized in investigations in social epidemiology: sex, age, education, occupation, housing, income and household size. This composite questionnaire will be used for qualitative analysis. | 6 month |
| Issoire |
| 63503 |
| France |
| AP-HM - Hôpital Nord | Marseille | 13015 | France |
| AP-HM - La Timone | Marseille | 13385 | France |
| HIA Laveran | Marseille | 13915 | France |
| Centre Hospitalier La Palmosa | Menton | 06507 | France |
| Centre Hospitalier Universitaire de Nice | Nice | 06003 | France |
| Centre Hospitalier Louis Giorgi | Orange | 84106 | France |
| Hôpital Lariboisière | Paris | 75010 | France |
| Hôpital Pitié-Salpêtrière | Paris | 75013 | France |
| Hôpital Bichat-Claude Bernard | Paris | 75018 | France |
| Hôpital Tenon | Paris | 75020 | France |
| Hôpital Cochin | Paris | 75679 | France |
| Centre hospitalier de Saint-Denis | Saint-Denis | 93200 | France |
| Centre Hospitalier de Vaison-la-Romaine | Vaison-la-Romaine | 84110 | France |
| Centre Hospitalier Jules Niel | Valréas | 84600 | France |
| Centre Hospitalier Jacques Lacarin | Vichy | 03207 | France |
| Centre Hospitalier Princesse Grace | Monaco | 98000 | Monaco |
| ID | Term |
|---|---|
| D011008 | Pneumococcal Infections |
| D004630 | Emergencies |
| ID | Term |
|---|---|
| D013290 | Streptococcal Infections |
| D016908 | Gram-Positive Bacterial Infections |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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