Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma

Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma

The purpose of this study is to determine the effect of antioxidant vitamins (vitamins C and E) on the development of coagulation derangements and nosocomial pneumonia after severe trauma in patients.

Inclusion Criteria:

• Adult trauma patients admitted to the emergency department at the University of Alabama at Birmingham (UAB) Hospital
• Blunt or penetrating injury
• UAB highest trauma activation

Exclusion Criteria:

• Age < 19 years of age
• Patients with known bleeding diathesis or who are concurrently taking anticoagulant medication
• Patients with known liver disease
• Minor patients
• Pregnant patients (known or suspected pregnancy)
• Patients who are incarcerated
• Patients who lack a surrogate