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Forward-looking troop established(constituted) by the patients having been included in the study " PADIS EP ", PHRC on 2006 and 2009, randomized checked(controlled), double-blind, comparing an anticoagulating treatment(processing) extended by coumadine versus placebo during 18 months at patients having had a first episode of EP idiopathique treated(handled) initially 6 months by anti-vitamin K.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HTPPE | Other | No drug and no placebo were used in this study. For all the patients who participated at the study PADIS-EP, somme exams must be performed. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HTPPE | Other | No drug and no placebo were used in this study. Some exams must be performed (DLCO - evaluation of the dyspnoea and pulmonary scintigraphy), and in function of the result of the pulmonary scintigraphy, the medical care of the patient will be different : negative pulmonary scintigraphy, stop of the explorations and taken care usual of the patients; positive pulmonary scintigraphy,realisation of a cardiac echography to estimate the presence or not of a not very probable, possible or likely HTP. The indication of the right cardiac catheterization is then put on the combination of the results of the cardiac echography and the evaluation of the dyspnoea. |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency of a HTPPE | 24 months |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality and cause | 24 months |
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Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Francis COUTURAUD, PU-PH | CHRU de Brest | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHRU de Brest | Brest | 29609 | France | |||
| CHU Clermont-Ferrand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36017744 | Derived | Fauche A, Presles E, Sanchez O, Jais X, Le Mao R, Robin P, Pernod G, Bertoletti L, Jego P, Parent F, Lemarie CA, Leven F, Le Roux PY, Salaun PY, Nonent M, Girard P, Lacut K, Savale L, Melac S, Guegan M, Mismetti P, Laporte S, Leroyer C, Montani D, Couturaud F, Tromeur C; PADIS-PE Investigators. Frequency and predictors for chronic thromboembolic pulmonary hypertension after a first unprovoked pulmonary embolism: Results from PADIS studies. J Thromb Haemost. 2022 Dec;20(12):2850-2861. doi: 10.1111/jth.15866. Epub 2022 Sep 25. |
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|
| Clermont-Ferrand |
| 63003 |
| France |
| CH de Lannion | Lannion | 22300 | France |
| Hôpital Européen Georges Pompidou | Paris | 75908 | France |
| CHU Pontchaillou - Hôpital Sud | Rennes | 35056 | France |
| Hôpital Yves Le Foll | Saint-Brieuc | 22027 | France |
| Hôpital de Bellevue - CHU de Saint-Etienne | Saint-Etienne | 45055 | France |
| Hôpital Rangueuil | Toulouse | 31059 | France |