Multistimulation Group Therapy for Alzheimer's Disease

Multistimulation Group Therapy in Mild to Moderate Alzheimer's Disease

Our previous findings support the notion that group activity program, based on cognitive stimulation, recreational-occupational activities and physical-psychomotor exercises, can lead to an improvement in behavioral aspects for people with Alzheimer's Disease (AD).

The purpose of this study is to clarify the efficacy of a rehabilitation program in outpatients affected by AD in mild to moderate stages.

Inclusion Criteria:

• diagnosis of possible/probable AD
• mild to moderate stage of AD (MMSE score of 15 - 24)and CDR score of 1-2
• range years in age (65-85) and in school attendance (5-17)
• right handed

Exclusion Criteria:

• severe aphasia (Token test score < 20)
• severe auditory and/or visual loss
• overt severe behavioral disturbances (delusions, hallucinations, agitation)
• recent (three month before the MST) introduction or dose modification of the following pharmacological treatments: cholinesterase inhibitor, memantine, antidepressant or antipsychotic drugs.