Coronary Heart Disease Risk in Type 2 Diabetes

A Randomised Control Trial (RCT) to Investigate the Effectiveness of a Selfmanagement Intervention and Personalised Genetic Risk Information to Reduce Risk of Coronary Heart Disease in Patients With Type 2 Diabetes.

The primary objective of the CORDIA study is to use an effective evidence-based self-management intervention (SMI) for type 2 diabetes, with and without a novel test to give a personalised genetic and lifestyle risk of coronary heart disease, to examine their capacity to reduce the risk of coronary heart disease (CHD) and improve diabetes management in primary care patients with type 2 diabetes. The effect of these interventions on clinical, behavioural and psychological outcomes will be investigated.

Inclusion Criteria:

• Males and females aged 25-70 years diagnosed with type 2 diabetes
• White, Afro-Caribbean or Asian-Indian ethnicity
• Most previous or baseline HbA1c ≥6.5% or 48 mmol/mol
• Fluency in written and spoken English

Exclusion Criteria:

• Diagnosis of ischemic heart disease, stroke, Transient Ischaemic Attack (TIA) or peripheral vascular disease
• Serious or enduring mental health problems that would prevent the patient from completing the study
• Currently receiving treatment for a life-threatening condition (e.g., cancer) or in the terminal stages of a condition
• Adults who cannot consent for themselves