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A randomized clinical trial to check the antipyretic efficacy of oral and intravenous paracetamol and intramuscular diclofenac sodium in patients presenting with fever to emergency department.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| oral paracetamol | Active Comparator | patients in this arm will receive 1000mg of oral paracetamol |
|
| Intravenous paracetamol | Active Comparator | patients in this arm will receive 1000 mg of intravenous paracetamol |
|
| Intramuscular Diclofenac | Active Comparator | patients in this arm will receive 75 mg of intramuscular diclofenac sodium |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oral paracetamol | Drug | after giving medicine temperature is checked every 30 minutes for 2 hours |
|
| Measure | Description | Time Frame |
|---|---|---|
| Reduction in temperature in every thirty minutes till 120 minutes after receiving antipyretics | Once the patients fulfill the inclusion criteria, they are randomly assigned to receive one of the three medications in the study ( oral paracetamol, intravenous paracetamol or intramuscular diclofenac). Baseline temperature is recorded using a standard thermometer. Then reduction in temperature is recorded every 30 minutes for 2 hours. | Reduction in temperature is checked every 30 minutes for a maximum of 120 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| osama H Mohammed | Hamad Medical Corporation | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hamad medical corporation | Doha | 3050 | Qatar |
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| Intravenous paracetamol | Drug | after giving medicine temperature is checked every 30 minutes for 2 hours |
|
| Intramuscular diclofenac | Drug | after giving medicine temperature is checked every 30 minutes for 2 hours |
|
| ID | Term |
|---|---|
| D005334 | Fever |
| D004630 | Emergencies |
| ID | Term |
|---|---|
| D001832 | Body Temperature Changes |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
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| ID | Term |
|---|---|
| D000082 | Acetaminophen |
| ID | Term |
|---|---|
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |
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