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As of 12/18/2017 notification of early closure of the trial due to lack of recruitment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PRGF-Endoret | Experimental |
| |
| Saline Solution | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PRGF-Endoret | Device | PRGF-Endoret mesotherapy micro injection. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in Hair density at three months (number of hairs per cm2) | Hair density (number of hairs per cm2) will be measured for each treatment group | 3 months post-treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Hair Width (micrometers) | Hair width will be measured for each treatment group | Basal, 1, 2, and 3 months post-treatment |
| Anagen/telogen ratio | Hair cycle has different phases. Two of the most important are anagen (active growth phase of hair follicles) and telogen (resting phase of the hair follicle). This secondary outcome measure allows to measure the efficacy of the PRGF-Endoret treatment. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ClÃnica Eduardo Anitua. | Vitoria-Gasteiz | Alava | 01007 | Spain | ||
| Centro dermatológico estético |
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| ID | Term |
|---|---|
| D000505 | Alopecia |
| ID | Term |
|---|---|
| D007039 | Hypotrichosis |
| D006201 | Hair Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| D000077330 | Saline Solution |
| ID | Term |
|---|---|
| D000077324 | Crystalloid Solutions |
| D007552 | Isotonic Solutions |
| D012996 | Solutions |
| D004364 | Pharmaceutical Preparations |
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| Saline Solution |
| Other |
Saline Solution mesotherapy micro injection |
|
| Basal, 1, 2, and 3 months post-treatment |
| Terminal Hair Density | Terminal hair density will be established for each one of the treatments | Before each one of the treatments and 1, 2 and 3 months post-treatment. |
| Vellous hair density | Vellous hair will be measured for each treatment group | Basal,1, 2 and 3 months post-treatment |
| Alicante |
| 03014 |
| Spain |
| D020763 |
| Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |