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| Name | Class |
|---|---|
| VisionTree | UNKNOWN |
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The RSSearch® Registry is an international multi-year database designed to track SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) utilization, treatment practices and outcomes to help determine, over time, the most effective use of these systems in management of patients with life threatening tumors and other diseases. (This study was formally called ReCKord and included the CyberKnife only; The ReCKord study continues as a CyberKnife subset of RSSearch.)
The Registry is designed to help SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) users to understand utilization of and key treatment outcomes for these treatment approaches. Some of the objectives include:
Allow participants to record information about usage of SRS/SBRT in everyday practice, including patient characteristics and disease information, treatment plans and outcomes Provide participants with ready access to data for publication of their own experience and as a tool for establishing collaborations with other participating sites Facilitate quality improvement efforts for individual treatment providers Understand the effectiveness of different treatment plans for different types of lesions, diseases and treatments
The Registry tracks select outcomes for each condition treated by SRS/SBRT (for example, PSA for prostate cancer); the Registry also provides individual participants the ability to add additional outcomes for each and any condition of specific interest to their institutions.
The Registry is hosted by Vision Tree, Inc who is an independent vendor of electronic registries; they are responsible for HIPAA compliance, including all security mechanisms.
Patients will be enrolled prospectively. Some retrospective patient data is likely to be included in order to capture both short and longer term outcomes data.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients being treated by SRS/SBRT | Patients with a condition being considered for treatment by SRS/SBRT |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| SRS/SBRT | Radiation | Intervention varies by condition being treated. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Overall survival | Survival from time of treatment to death | Up to 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Local and distant recurrence | Calculated from time of treatment to recurrence | One to Five years |
| Measure | Description | Time Frame |
|---|---|---|
| Treatment toxicity | Complications of treatment. These complications are organ specific depending on which organ is being treated. For example, if the prostate is being treated,there may be rectal and urinary complications. If the brain is being treated, there may be headaches or nausea. The Radiation Therapy Oncology Group (RTOG) scale used for defining and measuring complications of radiotherapy is incorporated into the Registry database. |
Inclusion Criteria:
Exclusion Criteria:
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Any patients who have a SRS/SBRT procedure
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jan Jenkins, RN | Contact | jjenkins@therss.org | ||
| Joanne Davis, PHD | Contact | jdavis@therss.org |
| Name | Affiliation | Role |
|---|---|---|
| Anand Mahadevan, MD | The Radiosurgery Society | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Penrose Cancer Center | Enrolling by invitation | Colorado Springs | Colorado | 80907 | United States | |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21735562 | Background | Tipton KN, Sullivan N, Bruening W, Inamdar R, Launders J, Uhl S, Schoelles KM. Stereotactic Body Radiation Therapy [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2011 May. Report No.: 10(11)-EHC058-EF. Available from http://www.ncbi.nlm.nih.gov/books/NBK55723/ | |
| 21625154 | Background |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_ICF | Yes | No | Yes | Study Protocol and Informed Consent Form | Jul 19, 2022 |
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| Immediate -5 years |
| Sylvester Comprehensive Cancer Center, University of Miami |
| Recruiting |
| Miami |
| Florida |
| 33146 |
| United States |
|
| Southeast Georgia Health System | Enrolling by invitation | Brunswick | Georgia | 31520 | United States |
| Henry Ford Health System | Recruiting | Detroit | Michigan | 48202 | United States |
|
| AtlantiCare Regional Medical Center and AtlantiCare Cancer Care Institute | Enrolling by invitation | Egg Harbor | New Jersey | 08234 | United States |
| Riverview Medical Center | Enrolling by invitation | Red Bank | New Jersey | 07701 | United States |
| NJ Cyberknife at Community Medical Center | Enrolling by invitation | Toms River | New Jersey | 08755 | United States |
| Montefiore Medical Center | Enrolling by invitation | The Bronx | New York | 10502 | United States |
| Geisinger Health System | Enrolling by invitation | Danville | Pennsylvania | 17822 | United States |
| Philadelphia CyberKnife | Enrolling by invitation | Philadelphia | Pennsylvania | 19083 | United States |
| Pottstown Memorial Medical Center | Enrolling by invitation | Pottstown | Pennsylvania | 19464 | United States |
| Cyberknife at Erlanger | Enrolling by invitation | Chattanooga | Tennessee | 37403 | United States |
| St. Mary's Medical Center | Enrolling by invitation | Huntington | West Virginia | 25701 | United States |
| Dieterich S, Gibbs IC. The CyberKnife in clinical use: current roles, future expectations. Front Radiat Ther Oncol. 2011;43:181-194. doi: 10.1159/000322423. Epub 2011 May 20. |
| 22236681 | Background | Wowra B, Muacevic A, Tonn JC. CyberKnife radiosurgery for brain metastases. Prog Neurol Surg. 2012;25:201-9. doi: 10.1159/000331193. Epub 2012 Jan 6. |
| 22498085 | Background | Sarwate D, Sarkar S, Krimsky WS, Burgan CM, Patel K, Evans R, Harley DP. Optimization of mediastinal staging in potential candidates for stereotactic radiosurgery of the chest. J Thorac Cardiovasc Surg. 2012 Jul;144(1):81-6. doi: 10.1016/j.jtcvs.2012.03.004. Epub 2012 Apr 11. |
| 22396835 | Background | Sohn S, Chung CK. The role of stereotactic radiosurgery in metastasis to the spine. J Korean Neurosurg Soc. 2012 Jan;51(1):1-7. doi: 10.3340/jkns.2012.51.1.1. Epub 2012 Jan 31. |
| 25975848 | Background | Davis JN, Medbery C, Sharma S, Pablo J, Kimsey F, Perry D, Muacevic A, Mahadevan A. Stereotactic body radiotherapy for centrally located early-stage non-small cell lung cancer or lung metastases from the RSSearch((R)) patient registry. Radiat Oncol. 2015 May 15;10:113. doi: 10.1186/s13014-015-0417-5. |
| 25774243 | Background | Davis JN, Medbery C 3rd, Sharma S, Perry D, Pablo J, D'Ambrosio DJ, McKellar H, Kimsey FC, Chomiak PN, Mahadevan A. Stereotactic body radiotherapy for early-stage non-small cell lung cancer: clinical outcomes from a National Patient Registry. J Radiat Oncol. 2015;4(1):55-63. doi: 10.1007/s13566-014-0177-0. Epub 2015 Jan 31. |
| 24274599 | Background | Davis JN, Medbery C 3rd, Sharma S, Danish A, Mahadevan A. The RSSearch Registry: patterns of care and outcomes research on patients treated with stereotactic radiosurgery and stereotactic body radiotherapy. Radiat Oncol. 2013 Nov 25;8:275. doi: 10.1186/1748-717X-8-275. |
| 28143558 | Background | Ricco A, Davis J, Rate W, Yang J, Perry D, Pablo J, D'Ambrosio D, Sharma S, Sundararaman S, Kolker J, Creach KM, Lanciano R. Lung metastases treated with stereotactic body radiotherapy: the RSSearch(R) patient Registry's experience. Radiat Oncol. 2017 Feb 1;12(1):35. doi: 10.1186/s13014-017-0773-4. |
| 26798571 | Background | Davis J, Sharma S, Shumway R, Perry D, Bydder S, Simpson CK, D'Ambrosio D. Stereotactic Body Radiotherapy for Clinically Localized Prostate Cancer: Toxicity and Biochemical Disease-Free Outcomes from a Multi-Institutional Patient Registry. Cureus. 2015 Dec 4;7(12):e395. doi: 10.7759/cureus.395. |
| 27182468 | Background | Singh R, Davis J, Sharma S. Stereotactic Radiosurgery for Trigeminal Neuralgia: A Retrospective Multi-Institutional Examination of Treatment Outcomes. Cureus. 2016 Apr 3;8(4):e554. doi: 10.7759/cureus.554. |
| 29439707 | Derived | Mahadevan A, Blanck O, Lanciano R, Peddada A, Sundararaman S, D'Ambrosio D, Sharma S, Perry D, Kolker J, Davis J. Stereotactic Body Radiotherapy (SBRT) for liver metastasis - clinical outcomes from the international multi-institutional RSSearch(R) Patient Registry. Radiat Oncol. 2018 Feb 13;13(1):26. doi: 10.1186/s13014-018-0969-2. |
| Aug 16, 2022 |
| Prot_ICF_000.pdf |
| ID | Term |
|---|---|
| D009369 | Neoplasms |
| D014277 | Trigeminal Neuralgia |
| ID | Term |
|---|---|
| D020433 | Trigeminal Nerve Diseases |
| D005156 | Facial Neuralgia |
| D005155 | Facial Nerve Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D003389 | Cranial Nerve Diseases |
| D009422 | Nervous System Diseases |
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