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| ID | Type | Description | Link |
|---|---|---|---|
| Online Number: 9015 | Registry Identifier | Online Number: 9015 |
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Ureteral stones may be silent in 5.3% of patients. The goal of this study was to prospectively evaluate the impact of a silent ureteral stone on renal function.
The prevalence of nephrolithiasis is increasing worldwide, reaching 5.2% in North America and 10.1% in Italy. The widespread use of computed tomography and ultrasonography have resulted in a greater detection rate of asymptomatic stones and, in part, might explain the trend. Clinically, kidney or ureteral stones range in severity from asymptomatic to presenting with complete renal failure. Therefore, it is not only the alarming incidence of urinary stone disease, but also the associated burden that makes this one of the most concerning conditions in public health.
The situation becomes even more distressing when managing asymptomatic stones. Studies of the natural history of stones have revealed that only 20% of patients yearly actually become symptomatic from a new stone, and one half of those require surgical intervention at some point. The guidelines are well established for the treatment of symptomatic urolithiasis, and many investigators have extensively studied the management of silent kidney stones. Conversely, the same is not true for silent ureterolithiasis. The purpose of the present study is to report the investigators experience managing silent ureteral stones and to prospectively analyze their true influence on renal function.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Surgical Treatment | Other | Silent Ureteral Stone - Surgical Treatment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Surgical Treatment | Procedure | Surgical Treatment - open, endoscopic or laparoscopic |
|
| Measure | Description | Time Frame |
|---|---|---|
| Ipsilateral Renal Function | Ipsilateral renal function determined by dimercaptosuccinic acid scintigraphy (DMSA) 12 months after surgery. | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Serum Creatinine level | Serum Creatinine level | 1 year |
| Estimated Creatinine Clearance | Estimated Creatinine Clearance | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Giovanni S Marchini, MD | Contact | 55-11-98179-8186 | giovanni_marchini@yahoo.com.br |
| Name | Affiliation | Role |
|---|---|---|
| Giovanni S Marchini, MD | University of Sao Paulo | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinics Hospital - University of Sao Paulo Medical School | Recruiting | São Paulo | São Paulo | 05403-000 | Brazil |
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| ID | Term |
|---|---|
| D014545 | Urinary Calculi |
| D002137 | Calculi |
| ID | Term |
|---|---|
| D052878 | Urolithiasis |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| ID | Term |
|---|---|
| D013514 | Surgical Procedures, Operative |
| D004724 | Endoscopy |
| D010535 | Laparoscopy |
| ID | Term |
|---|---|
| D003949 | Diagnostic Techniques, Surgical |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D019060 | Minimally Invasive Surgical Procedures |
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| Renal Anatomy assessed by Ultrasound | Renal Anatomy assessed by Ultrasound | 1 year |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |