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| Name | Class |
|---|---|
| Dairy Farmers of Canada | OTHER |
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This project evaluates the use of different types of proteins from various food sources after an exercise session, on muscle mass and physical capacity in aged sarcopenic men (who have low muscle mass). Specifically, researchers want to:
All participants are exercising (resistance training) and ingest one of the 3 different sources of proteins, immediately after training:
Our hypothesis is that proteins from milk will induce a gain in muscle mass and physical function equivalent to the essential amino acids (EAA). We anticipate that both milk proteins and EAA will be both superior to control group.
This would represent an interesting finding since milk is more accessible, palatable and cheaper than essential amino acids commercial mix.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Milk proteins | Experimental | This group will do a resistance training + milk proteins (milk beverage) |
|
| Essential amino acids (add to soya bvg) | Experimental | This group will do a resistance training + essential amino acids (added to soya beverage) |
|
| No protein (control) | Placebo Comparator | This group will do a resistance training + ingestion of the control beverage (no protein, rice beverage) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Resistance training | Other | All group will exercise 3x/week. Each session of resistance training will last 60min. and will target main muscular groups. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Muscle mass | At baseline and post intervention (17th week) |
| Measure | Description | Time Frame |
|---|---|---|
| Relative strength | At baseline and post intervention (17th week) | |
| Blood markers of inflammation | Plasmatic IL-6 anf TNF-alpha | At baseline and post intervention (17th week) |
| Measure | Description | Time Frame |
|---|---|---|
| Dietary intakes | 3-day food record - Control variable (in order to verify if changes we observe through the intervention are accountable or not for dietary intakes) | At baseline, mid (8th week) and post intervention (17th week) |
| Physical activity level |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Isabelle J. Dionne, Ph.D. | Université de Sherbrooke | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre de recherche sur le vieillissement | Sherbrooke | Quebec | J1H 4C4 | Canada |
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| ID | Term |
|---|---|
| D055948 | Sarcopenia |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D009133 | Muscular Atrophy |
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D055070 | Resistance Training |
| ID | Term |
|---|---|
| D005081 | Exercise Therapy |
| D012046 | Rehabilitation |
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
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| Plasma Lipid profile | Apolipoproteins (Apo-AI, Apo-AII, Apo-B); Total cholesterol, HDL, LDL and triglycerides. | At baseline and post intervention (17th week) |
| Plasma creatinine | Blood marker on renal function will be assessed to ensure the safety of the supplementation of protein intake on renal function in sarcopenic men. | At baseline, mid (8th week) and post intervention (17th week) |
| Blood markers of fatty liver | Alanine aminotransferase (ALT), Aspartate aminotransferase (AST), Gamma-glutamyltransferase (GGT) and Alkaline phosphatase (ALP). | At baseline and post intervention (17th week) |
| extracellular HSP72 | At baseline and post intervention (17th week) |
Physical Activity Scale for the Elderly (PASE) - Control variable (in order to verify if changes we observe through the intervention are accountable or not for daily physical activity level)
| At baseline and post intervention (17th week) |
| D001284 | Atrophy |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |
| D001519 | Behavior |
| D005791 |
| Patient Care |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D064797 | Physical Conditioning, Human |
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |