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| ID | Type | Description | Link |
|---|---|---|---|
| 2R42AG032748 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Aging (NIA) | NIH |
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BioSensics has developed a Physical Activity Monitoring System (PAMSys) that consists of a single wearable motion sensor that is worn on the torso. The objectives of this observational study are the following: 1) to test the efficacy of PAMSys for objectively assessing a persons risk of falling based on activity data measured during activities of daily living and 2) to test the efficacy of PAMSys for identifying precise early physical activity or functioning indicators of frailty in those who are pre-frail or frail as compared to non-frail controls.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| non-frail | Categorized as non-frail based on Fried's five phenotypic criteria (Fried L.P., et al. Frailty in Older Adults: Evidence for a Phenotype. Journal of Gerontology: 2001, Vol. 56A, No. 3, M146-M156) | ||
| pre-frail | Categorized as pre-frail based on Fried's five phenotypic criteria (Fried L.P., et al. Frailty in Older Adults: Evidence for a Phenotype. Journal of Gerontology: 2001, Vol. 56A, No. 3, M146-M156) | ||
| frial | Categorized as frail based on Fried's five phenotypic criteria (Fried L.P., et al. Frailty in Older Adults: Evidence for a Phenotype. Journal of Gerontology: 2001, Vol. 56A, No. 3, M146-M156) |
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| Measure | Description | Time Frame |
|---|---|---|
| Average sit-to-stand transition time over 48-hour monitoring period | Eligible subjects will receive a PAMSys motion sensors and necessary instructions for proper use. They will then wear the motion sensor continuously for 48 hours. PAMSys will record the duration of each sit-to-stand transition during this 48 hour monitoring period. The primary outcome measure is the average of these durations. | Averaged over days 1 and 2 |
| Measure | Description | Time Frame |
|---|---|---|
| Average stand-to-sit transition time during 48 hours of continuous monitoring | Eligible subjects will receive a PAMSys motion sensors and necessary instructions for proper use. They will then wear the motion sensor continuously for 48 hours. PAMSys will record the duration of each stand-to-sit transition during this 48 hour monitoring period. The primary outcome measure is the average of these durations. |
| Measure | Description | Time Frame |
|---|---|---|
| Fraility as categorized based on Fried's five phenotypic criteria | Fried L.P., et al. Frailty in Older Adults: Evidence for a Phenotype. Journal of Gerontology: 2001, Vol. 56A, No. 3, M146-M156 | First evaluation (day 1) |
| Fraility as categorized based on Fried's five phenotypic criteria |
Inclusion Criteria:
Exclusion Criteria:
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Pima County Arizona elders aged 65+ will be recruited from the Arizona Center on Aging affiliated geriatrics clinics.
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| Name | Affiliation | Role |
|---|---|---|
| Joseph Gwin, PhD | BioSensics | Principal Investigator |
| Bijan Najafi, PhD | University of Arizona | Principal Investigator |
| Jane Mohler, PhD | University of Arizona | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Arizona Center on Aging | Tucson | Arizona | 85719 | United States | ||
| Baylor College of Medicine Interdisciplinary Consortium on Advance Motion Performance |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37231977 | Derived | Pradeep Kumar D, Najafi B, Laksari K, Toosizadeh N. Sensor-Based Assessment of Variability in Daily Physical Activity and Frailty. Gerontology. 2023;69(9):1147-1154. doi: 10.1159/000530900. Epub 2023 May 10. | |
| 32930988 | Derived | Pradeep Kumar D, Wendel C, Mohler J, Laksari K, Toosizadeh N. Between-day repeatability of sensor-based in-home gait assessment among older adults: assessing the effect of frailty. Aging Clin Exp Res. 2021 Jun;33(6):1529-1537. doi: 10.1007/s40520-020-01686-x. Epub 2020 Sep 15. |
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| Averaged over days 1 and 2 |
Fried L.P., et al. Frailty in Older Adults: Evidence for a Phenotype. Journal of Gerontology: 2001, Vol. 56A, No. 3, M146-M156 |
| 6 months |
| Houston |
| Texas |
| 77030 |
| United States |
| 32375700 | Derived | Pradeep Kumar D, Toosizadeh N, Mohler J, Ehsani H, Mannier C, Laksari K. Sensor-based characterization of daily walking: a new paradigm in pre-frailty/frailty assessment. BMC Geriatr. 2020 May 6;20(1):164. doi: 10.1186/s12877-020-01572-1. |
| 28285311 | Derived | Parvaneh S, Mohler J, Toosizadeh N, Grewal GS, Najafi B. Postural Transitions during Activities of Daily Living Could Identify Frailty Status: Application of Wearable Technology to Identify Frailty during Unsupervised Condition. Gerontology. 2017;63(5):479-487. doi: 10.1159/000460292. Epub 2017 Mar 11. |