New data was published in the literature

Following medical history and clinical examination the children which are scheduled for treatment with suspected pulpary involved primary teeth will be selected. During the regular treatment if a pulp of primary teeth is opened and before the regular pulpotomy procedure is performed the blood that is flowing out of the pulp will be collected and stored until analyzed for the present of inflammatory markers. Clinical and radiographic evaluation will be obtained in follow up appointments if the child will remain in regular treatments in our clinic.

Inclusion Criteria:

- Pulpal involved primary teeth with a vital pulp of which a certain amount of blood can be obtained.

Exclusion Criteria:

• systemic disease
• pulp necrosis
• permanent teeth

Children undergoing pulpotomy during regular dental treatment