High Flow Therapy vs Hypertonic Saline in Bronchiolitis

High Flow Therapy vs Hypertonic Saline in Bronchiolitis Treatment. Randomized Controlled Trial

The purpose of this study is to demonstrate that heated, humidified, high-flow nasal cannula (HHHFNC) is superior to hypertonic saline solution (HSS) in the treatment of moderate acute viral bronchiolitis in infants in improving respiratory distress and comfort and reducing length of hospital stay (LOS) and admission to Pediatric Intensive Care Unit (PICU).

Inclusion Criteria:

• Children aged 6 months or less
• Moderate (Respiratory Distress Assessment Instrument score of 4 or greater) viral bronchiolitis (as defined by McConnockie)
• Meeting Admission criteria

Exclusion Criteria:

• History of prematurity
• Chronic lung disease
• Cystic fibrosis
• Congenital heart disease
• Neuromuscular disease
• Airway anomalies
• Immunodeficiency
• Those requiring immediate intubation and ventilation.