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| Name | Class |
|---|---|
| The Lawson Foundation | OTHER |
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Gestational diabetes mellitus (GDM) complicates 5 to 30 % of pregnancies. GDM is defined as hyperglycemia with onset or first recognition during pregnancy. Because it is a forerunner of type 2 diabetes mellitus (T2DM), professional associations recommend T2DM postpartum screening (T2DM-pPS) at 6 weeks/6 months post delivery, using a 75g oral glucose tolerance test (OGTT).
However, less than a quarter of these women are screened. This recommendation has failed for multiple reasons; the most important being that busy new mothers must deal with the major inconveniences of returning to a sampling center for a 2h testing session, bringing baby along or paying for a sitter, transportation, parking… A mother-friendly solution is direly needed.
The investigators hypothesize that, in these women, results of an OGTT performed after delivery on the last day of their hospital stay (OGTT-1) will predict results of the recommended OGTT (OGTT-2) at 6 weeks/6 months postpartum.
The main aim of our project is to determine the optimal cut-off value for the 2h glucose result during OGTT-1 in order to predict abnormal glucose tolerance status at OGTT-2 (the gold standard), in the same woman.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| postpartum screening | Experimental | Oral glucose tolerance test 2 days post-partum |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| oral glucose tolerance test 2 days post-partum | Procedure | Screening for type 2 diabetes after gestational diabetes mellitus. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Diagnosis of abnormal glucose tolerance | Oral glucose tolerance test | 12 weeks postpartum |
| Measure | Description | Time Frame |
|---|---|---|
| Patient's satisfaction | Satisfaction questionnaire | 12 weeks post-partum |
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Inclusion Criteria:
Exclusion Criteria:
History of glucose intolerance or diabetes before the pregnancy;
Have presented another obstetrical pathology during the pregnancy;
Moderate to severe postpartum bleeding;
Surgery in postpartum (curettage, hysterectomy, etc.).
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| Name | Affiliation | Role |
|---|---|---|
| Jean-Luc Ardilouze, MD, PhD | Clinical Research Center Étienne-Le Bel of the Sherbrooke University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinical Research Center Étienne-Le Bel of the Sherbrooke University Hospital | Sherbrooke | Quebec | J1H 5N4 | Canada |
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| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D005951 | Glucose Tolerance Test |
| D049590 | Postpartum Period |
| ID | Term |
|---|---|
| D001774 | Blood Chemical Analysis |
| D019963 | Clinical Chemistry Tests |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
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| D004700 | Endocrine System Diseases |
| D003933 | Diagnosis |
| D003940 | Diagnostic Techniques, Endocrine |
| D008919 | Investigative Techniques |
| D055703 | Reproductive Physiological Phenomena |
| D012101 | Reproductive and Urinary Physiological Phenomena |