Clinical Evaluation of Systane® ULTRA Compared to OPTIVE® in Ocular Surface Staining

Clinical Evaluation of Systane® ULTRA Compared to OPTIVE® in Ocular Surface Staining

The purpose of this study is to compare Systane® ULTRA lubricant eye drops to OPTIVE® lubricating eye drops for ocular surface staining within dry eye subjects and to evaluate the safety of Systane® ULTRA after 3 months of use.

Following a 2-week washout phase with saline eye drops, subjects were randomized to receive either Systane® ULTRA or OPTIVE® for the remainder of the study.

Inclusion Criteria:

• Willing and able to attend all study visits.
• Diagnosis of dry eye, as specified in protocol.
• Uses artificial tears, as specified in protocol.
• Other protocol-defined inclusion criteria may apply.

Exclusion Criteria:

• Poor visual acuity, as specified in protocol.
• Women of childbearing potential who are pregnant, lactating, or not using adequate birth control, as specified in protocol.
• Any hypersensitivity or allergy to the investigational products or ingredients.
• Any eye disorder, ocular surgery, medication, medical condition, or systemic disease, as specified in protocol.
• Contact lens use within 2 weeks of Screening Visit.
• Other protocol-defined exclusion criteria may apply.