To evaluate the change in patient pain perception with the use of a topical compounded pain cream regimen.

This is a prospective,observational,single center, open label study of patients that receive a combination topical compounded analgesic medication with no comparator group.

Inclusion Criteria:

• Participants must be diagnosed with an ICD9 code indicative of chronic pain.
• Participants must be starting a new regimen of topical therapy with multiple compounded agents.
• Participants must be expecting to receive therapy for at least 12 weeks.
• Participants must be between 18 and 65 years of age.
• Participants must be able to provide sound written and verbal informed consent.

Exclusion Criteria:

• Participants must not have prior hypersensitivity or adverse events to any of the components in the customized prescription.
• Participants must not be pregnant or breastfeeding women.
• Participants must not have a diagnosis of cancer within the past 5 years.

Participants with neuropathic or nociceptive chronic pain who are between 18 and 65 years of age prescribed a combination compounded topical analgesic.