The primary purpose of the protocol is to evaluate the StO2 performance measured at the admission to the emergency department to identify hemodynamic failure at the admission or within the first three hours of monitoring patients with drug poisoning.

The study hypotheses are:

• The early detection of hypoperfusion by StO2, essential to prevent the development of collapse.
• To limit hemodynamic failure effects, reduce morbidity and mortality of drug poisoning, hospital stay and cost.

The procedure is a measurement and non-invasive monitoring system of percentage of oxygen saturation of haemoglobin in tissues using infrared technology. The system used in the study is the tissue oxygenation monitor InSpectraTM StO2 Spot Check, Model 300 consisting of a clamp applied to the base of the thumb of the patient.

Inclusion Criteria:

• admitted to the emergency department,
• whose pattern of hospitalization is drug poisoning, defined on data from the patient's interrogation or his family if the patient is not able to answer,
• Written informed consent signed by the patient or, if he's unable to sign, by a companion,
• Affiliated to medical insurance

Exclusion Criteria:

• Patients without thenar eminence or having a disease of the thenar,
• Refusal to participate in the study,
• Participation in another biomedical research,
• Patient under guardianship, trusteeship or judicial protection,
• Pregnant women or nursing mothers