Iron Supplementation for Acute Anemia After Postbariatric Abdominoplasty

Iron Supplementation for Acute Anemia After Postbariatric Abdominoplasty: a Randomized Controlled Trial

The purpose of this study is to determine whether intravenous or oral iron are effective in the treatment of postoperative anemia and iron deficiency in patients submitted in postbariatric abdominoplasty.

Multicenter open randomized clinical trial with allocation ratio 1: 1. 56 adult patients undergoing post- bariatric abdominoplasty will be evaluated. The study group will receive 200 mg of intravenous iron in the immediate postoperative period and a second application on day 1 postoperatively. The control group will receive 100 mg of oral iron twice daily for 8 weeks. Haematological variables , iron 's profile , quality of life ( SF -36 and FACT- An) and adverse events will be assessed preoperatively and on the first , fourth and eighth weeks postoperatively .

Inclusion Criteria:

• Women
• 18 a 55 years
• Prior open or laparoscopic standard limb Roux and Y gastric bypass
• BMI < 32 kg/m2
• Stability of weight loss for at least 6 months
• grade 3 abdominal deformity on the Pittsburgh scale

Exclusion Criteria:

• Illiterate
• Current smoking
• Prior IV iron use in the last 3 months
• Uncontrolled systemic diseases
• Hemoglobin < 11 g/dL
• Ferritin <11 ng/mL
• Ferritin > 100 ng/mL
• transferrin saturation <16%
• transferrin saturation> 50%
• B12 < 210 pg/mL
• Folic Acid < 3.3 ng/mL
• Albumin < 2 g/dL
• C reactive protein> 5 mg/L
• Prior Anaphylactic reaction to IV iron