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| Name | Class |
|---|---|
| Child and Adolescent Psychiatry, Stockholm | INDUSTRY |
| Region Stockholm | OTHER_GOV |
| Stiftelsen Sunnerdahls Handikappfond | OTHER |
| The Swedish Research Council |
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This trial investigates the behavioral effects of manualized social skills training (KONTAKT) in children´s and adolescents with high-functioning autism spectrum disorder with psychiatric comorbidity in a RCT, multicenter study. N = 288 are recruited from 10 child and adolescent psychiatric clinics in Stockholm County. The examination of genetic variants as predictors for outcome and a qualitative study of KONTAKT complete the trial.
There are few randomized controlled trials of social skills group training for the Children's and adolescents with high functioning autism spectrum disorders (HFA)(1). The Objective of this trial is to investigate the behavioral effects of the manualized social skills group training KONTAKT (2,3) and the role of genetic variants for training effects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Social skills group training KONTAKT | Experimental | N= 144 participants are offered group training KONTAKT. The intervention includes 12 (brief intervention) and 24 (long intervention) sessions. |
|
| Control group (TAU), the usual intervention / treatment | No Intervention | N = 144 participants are received treatment as usual (pharmacological therapy, family therapy, Cognitive behavioral therapy etc). |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Social skills group training, KONTAKT | Behavioral | KONTAKT is a manual-based social skills group training for children with high functioning autism spectrum disorder (ASD). The program is based on cognitive behavioral therapy (CBT) principles and knowledge of social cognition. The group treatment includes exercises in social skills as well as discussions of social cognition, social interaction, self-reflection and description of themselves and others. The children are training to make contact, to understand and follow social rules, to become aware of themselves and others, to perceive verbal and nonverbal signals in a communication, to develop problem solving skills and coping strategies to manage conflict and to enhance their self-confidence. Intervention includes 12 (brief intervention) and 24 (long intervention) sessions. Each group consists of 4-8 children/adolescents ant two group leaders. The treatment are conducted in cooperation with both parents and teachers. |
| Measure | Description | Time Frame |
|---|---|---|
| Social Responsiveness Scale (SRS) | Parent and teachers report. | Baseline, 3 months after training and 3 months follow-up |
| Measure | Description | Time Frame |
|---|---|---|
| Adaptive Behavior Assessment System II (ABAS II) | Parent and teachers report. | Baseline, 3 months after training and 3 months follow-up |
| Developmental Disabilities Modification of the Children's Global Assessment Scale (DD-CGAS) |
| Measure | Description | Time Frame |
|---|---|---|
| Perceived stress Scale (PSS) | Parent report. | Baseline, 3 months after training and 3 months follow-up |
| Barn Under Stress (BUS) | Self report. |
Inclusion criteria:
Exclusion criteria:
Any behavioral disorder not currently allowing meaningful participation in group-based training for ASD, e.g. presence of clinically diagnosed self-injury, conduct disorder (F91), hyperkinetic conduct disorder (F90.1), antisocial personality disorder (F60.2), borderline personality disorder (F60.3) or any form of schizophrenia or related psychotic disorder (F20-F29).
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| Name | Affiliation | Role |
|---|---|---|
| Sven Bölte, PhD, Professor | Karolinska Institutet, Center of Neurodevelopmental Disorders (KIND) | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Child & Adolescent Psychiatry Research Center, KIND | Stockholm | 11330 | Sweden |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Background | 1. Reichow B, Steiner A. M., Volkmar FR. Social skills groups for people aged 6 to 21 with autism spectrum disorders (ASD) (Review). Cochrane Developmental, Psychosocial and Learning Problems Group, 2012. DOI: 10.1002/14651858. | ||
| Background | 2. Bölte S., Choque-Olsson N., Swedish version, KONTAKT, Social färdighetsträning i grupp med fokus på kommunikation och social interaktion vid autismspektrumtillstånd enligt Frankfurtmodellen. Hogrefe, 2011. | ||
| 19165532 | Background | Herbrecht E, Poustka F, Birnkammer S, Duketis E, Schlitt S, Schmotzer G, Bolte S. Pilot evaluation of the Frankfurt Social Skills Training for children and adolescents with autism spectrum disorder. Eur Child Adolesc Psychiatry. 2009 Jun;18(6):327-35. doi: 10.1007/s00787-008-0734-4. Epub 2009 Jan 22. | |
| Label | URL |
|---|---|
| Homepage KIND | View source |
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| OTHER_GOV |
| The Pediatric Research Foundation at Astrid Lindgren Children's Hospital | OTHER |
| Majblomman | UNKNOWN |
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Experts report.
| Baseline, 3 months after training and 3 months follow-up |
| Clinical Global Impression-Improvement/Severity (CGI) | Experts report. | Baseline, 3 months after training and 3 months follow-up |
| Samples With DNA | Genetic material via saliva-kit will be collected. | 2 weeks after the beginning of the treatment |
| Baseline, 3 months after training and 3 months follow-up |
| Background |
| Choque Olsson N, Bolte S. Brief report: "Quick and (not so) dirty" assessment of change in autism: cross-cultural reliability of the Developmental Disabilities CGAS and the OSU autism CGI. J Autism Dev Disord. 2014 Jul;44(7):1773-8. doi: 10.1007/s10803-013-2029-y. |
| 28647010 | Background | Choque Olsson N, Flygare O, Coco C, Gorling A, Rade A, Chen Q, Lindstedt K, Berggren S, Serlachius E, Jonsson U, Tammimies K, Kjellin L, Bolte S. Social Skills Training for Children and Adolescents With Autism Spectrum Disorder: A Randomized Controlled Trial. J Am Acad Child Adolesc Psychiatry. 2017 Jul;56(7):585-592. doi: 10.1016/j.jaac.2017.05.001. Epub 2017 May 10. |
| 26912485 | Derived | Choque Olsson N, Rautio D, Asztalos J, Stoetzer U, Bolte S. Social skills group training in high-functioning autism: A qualitative responder study. Autism. 2016 Nov;20(8):995-1010. doi: 10.1177/1362361315621885. Epub 2016 Feb 24. |
| ID | Term |
|---|---|
| D000067877 | Autism Spectrum Disorder |
| D001289 | Attention Deficit Disorder with Hyperactivity |
| D001008 | Anxiety Disorders |
| D003863 | Depression |
| ID | Term |
|---|---|
| D002659 | Child Development Disorders, Pervasive |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
| D019958 | Attention Deficit and Disruptive Behavior Disorders |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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