A Test of the Comparison Between Trans-rectal and Trans-perineal Biopsy of Prostate

The purpose of this randomized controlled trial (RCT) is to compare the two ways (tras-rectal and trans-perineal) to perform prostate biopsy from the rate of Positive detection, complications, pain level, operation time and costs et al.

Inclusion Criteria:

• prostate-specific antigen > 4ng/ml
• Palpation is positive

Exclusion Criteria:

• older than 80y
• prostate-specific antigen > 100 ng/ml