Anticoagulant Utilization Pattern

A Description of Warfarin and NOAC Utilization Patterns Including Initiation, Switching, and Discontinuation

This study plans to describe utilization patterns for oral anticoagulants over time in patients with non-valvular atrial fibrillation at risk for stroke using electronic claims data from a United States commercial insurance database.

Inclusion criteria:

• A recorded diagnosis of atrial fibrillation
• Initiation of oral anticoagulant medication
• Congestive Heart Failure, Hypertension, Age > 75, Diabetes Mellitus, Prior Stroke or Transient Ischemic Attack, Vascular Disease, Age 65-74, Sex Category (CHA2DS2-VASc) Score >=1
• At least 18 years of age on the date of anticoagulant initiation

Exclusion criteria:

• Patients with missing or ambiguous age or sex information
• Patients with documented evidence of valvular disease
• Patients with less than 12 months enrolment in the UnitedHealth Research Database preceding the first dispensing
• Patients with prior use of any oral anticoagulant