Influence of High Intensity Exercise on Insulin Resistance, Muscle Contractile Properties, Aerobic Capacity and Body Composition in Multiple Sclerosis

Rehabilitation in MS: Influence of High Intensity Exercise on Insulin Resistance, Muscle Contractile Properties, Aerobic Capacity and Body Composition in Multiple Sclerosis

The purpose of this study is to investigate the effects of a combined training programme and a high intensity interval training programme on insulin resistance, muscle strength/ muscle contractile properties, aerobic capacity and body composition in MS patients.

It is assumed that the the above mentioned clinical parameters will improve due to physical exercise.

Inclusion Criteria:

• Diagnosed MS according to the McDonald criteria
• Expanded Disability Status Scale (EDSS) between 0.5 and 6
• Be able to train 5 times in 2 weeks at the University

Exclusion Criteria:

• Comorbidities like cardiovascular-, respiratory-, orthopaedic or metabolic diseases (like diabetes type 2)
• Having had an relapse in a period of 3 months prior to the start of the intervention period
• Having an relapse during the intervention period
• Pregnancy and other contra indications for physical activity
• Mental disorders