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Acute kidney injury after cardiac surgery has been reported to increase morbidity and mortality. Several risk scoring models for prediction of aortic kidney injury after cardiac surgery have been developed. However, predictive accuracy of these models is stil unclear. The aim of this study is to evaluate the accuracy of four pre-existing prediction models using a gray zone approach in patients who underwent aortic surgery in our institution.
Acute kidney injury after cardiac surgery has been reported to increase morbidity and mortality. Several risk scoring models for prediction of aortic kidney injury after cardiac surgery have been developed. However, predictive accuracy of these models is stil unclear. The aim of this study is to evaluate the accuracy of four pre-existing prediction models (AKICS, Wijeysundera, Mehta, and Thakar model)using a gray zone approach in patients who underwent aortic surgery in our institution. Based on receiver operating characteristic (ROC) curve analysis, we will construct a gray zone using the cut-off values with a sensitivity of < 90%, and a specificity of < 90% (diagnostic tolerance of 10%).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients who underwent aortic surgery | Patients who underwent aortic surgery in Samsung Medical Center during the period between 2004 and 2010 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| elective or emergency aortic surgery (including ascending, arch, descending thoracic aorta) | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| presence of acute kidney injury |
| within 48 hour after aortic surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Gray zone range of each risk scoring model | Thresholds with as a sensitivity of < 90% and a specificity of < 90%. | within 48 hours |
| Number of patients in the gray zone | Number of patients in the gray zone in each risk scoring model |
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Inclusion Criteria:
Exclusion Criteria:
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Those who underwent elective or emergency aortic surgery in Samsung Medical Center during between 2004 and 2010.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Samsung Medical Center, Sungkyunkwan University, School of Medicine | Seoul | 135-710 | South Korea |
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| within 48 hours after aortic surgery |
| ID | Term |
|---|---|
| D058186 | Acute Kidney Injury |
| ID | Term |
|---|---|
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
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| ID | Term |
|---|---|
| D017558 | Elective Surgical Procedures |
| D000082182 | Clonal Hematopoiesis |
| ID | Term |
|---|---|
| D013514 | Surgical Procedures, Operative |
| D006410 | Hematopoiesis |
| D002454 | Cell Differentiation |
| D002468 | Cell Physiological Phenomena |
| D060965 | Clonal Evolution |
| D055614 | Genetic Phenomena |
| D001790 | Blood Physiological Phenomena |
| D002943 | Circulatory and Respiratory Physiological Phenomena |
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