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| Name | Class |
|---|---|
| Korean Center for Disease Control and Prevention | OTHER_GOV |
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We want to examine the effect of multidisciplinary interventions in asthma patients who had experienced acute exacerbation of asthma.
In our previous observational studies, elderly asthma patients had a some distinct features such as impairment of cognitive function, deficiency of micronutrient and absence of caregiver compared with young adult asthmatics.
We wanted to evaluate whether the long-term course of asthma could be modified by intervening deficienies which were found in elderly patiensts.
So, we designed a interventional study to correct above risk factors in elderly asthma patients, which could be aggravating their asthma. Followings are our specific multidiciplinary items that we want to correct.
After 1 years, we will measure the numbers of acute exacerbations, lung function including FEV1 and FEV1/FVC, health-related quality of life and level of serum magnesium in study patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention | Experimental | We designed a intervention study to correct additional risk factors in elderly asthma patients. We offer following specific interventions simultaneously to intervention arm and will measure the effects of interventions after 1 years.
|
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Magnesium | Dietary Supplement |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of acute exacerbation of asthma | measure the existence of acute exacerbation when they visit the clinic at 3, 6, 12 month after enrollment | 1 year from enrollment |
| Measure | Description | Time Frame |
|---|---|---|
| Pulmonary function test | measure when subjects visits the clinic at 3, 6, 12 month after enrollment | 1 year after enrollment |
| Asthma control status | measure when subjects visit the clinic at 3, 6, 12 month after enrollment |
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Inclusion Criteria:
elderly asthma patients who had experienced acute exacerbation of asthma
1)aggravations of any of major criteria
dyspnea
cough
wheezing
increase or purulent changes of sputum
nocturnal symptoms
2)aggravation of more than one of following criteria
a reduction of forced expiratory volume at one second or peak expiratory flow rate more than 20% compared than one's best score
unscheduled clinic or emergency department visit or admission
step-up of dose of asthma medications or any intake of systemic steroids
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| Name | Affiliation | Role |
|---|---|---|
| Sang-Heon Cho, MD./PhD | Seoul National University Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Seoul | Seoul | 110-460 | South Korea |
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| ID | Term |
|---|---|
| D001249 | Asthma |
| D008275 | Magnesium Deficiency |
| ID | Term |
|---|---|
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
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| ID | Term |
|---|---|
| D008274 | Magnesium |
| D025101 | Vitamin B 6 |
| D004522 | Educational Status |
| D015277 | Hotlines |
| ID | Term |
|---|---|
| D008673 | Metals, Alkaline Earth |
| D004602 | Elements |
| D007287 | Inorganic Chemicals |
| D019565 | Metals, Light |
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| Education for asthma action plan | Behavioral |
|
| hot-lines for acute exacerbation of asthma | Behavioral |
|
| Inhaler technique training | Behavioral |
|
| one year from enrollment |
| asthma quality of life questionnaire | measure when subjects visit the clinic at 3, 6, 12 month after enrollment | one year from enrollment |
| serum magnesium level | measure when subjects visit the clinic at 3, 6, 12 month after enrollment | one year from enrollment |
| D012130 |
| Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| D003677 | Deficiency Diseases |
| D044342 | Malnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D008670 |
| Metals |
| D010847 | Picolines |
| D011725 | Pyridines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D012959 | Socioeconomic Factors |
| D011154 | Population Characteristics |
| D004632 | Emergency Medical Services |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |