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We will use Cilostazol as a tool to investigate its headache inducing effects in migraine patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cilostazol | Active Comparator | Capsule of Cilostazol 200 mg are taken orally on each study day |
|
| Placebo | Placebo Comparator | A capsule of placebo containing starch are taken orally on each study day. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cilostazol | Drug |
|
| |
| Placebo |
| Measure | Description | Time Frame |
|---|---|---|
| The incidens of headache or migraine after adminstration of Cilostazol in migraine patients compared to placebo. | Rectruitment of 14 patients will be done during April and May. Experiments will be carried out in May and June. Each experiment day takes 1½ hour. Data analysis will be done in June and July. Final data will be presented within 6 months. | Outcome measure will be done within 3 month. Final data will be presented within 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Danish Headache Center & Department of Neurology | Copenhagen | Glostrup | 2600 | Denmark |
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| ID | Term |
|---|---|
| D008881 | Migraine Disorders |
| ID | Term |
|---|---|
| D051270 | Headache Disorders, Primary |
| D020773 | Headache Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| ID | Term |
|---|---|
| D000077407 | Cilostazol |
| ID | Term |
|---|---|
| D013777 | Tetrazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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| Drug |
|
| D009422 | Nervous System Diseases |
| D011804 |
| Quinolines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |