ComVi and D-type Stent in Malignant GOO

A Newly Designed Conformable Uncovered Versus Covered Self-expandable Metallic Stent for Palliation of Malignant Gastric Outlet Obstruction: a Prospective, Randomized Multicenter Study

Covered self-expandable metallic stents (SEMS) have been used to prevent tumor ingrowth, a common complication of uncovered SEMSs. However, they have revealed a high incidence of stent migration in patients with unresectable malignant gastric outlet obstruction (GOO). A conformable covered SEMS was introduced to overcome both stent migration and tumor ingrowth. The aims of this study were to evaluate the clinical outcomes of newly designed conformable covered and uncovered SEMS for palliation of malignant GOO.

Inclusion Criteria:

• adults 18 years of age or older
• obstructive symptoms due to unresectable malignant GOO
• a Karnofsky performance score of more than 30 (13)

Exclusion Criteria:

• history of a previous SEMS insertion
• the presence of obstruction in the gastrointestinal tract excluding the gastric outlet
• severe comorbidities precluding the endoscopic procedure, such as cardiopulmonary disease, sepsis, and bleeding disorders
• a life expectancy of less than 1 month after SEMS insertion
• history of gastric surgery