This study seeks to compare the differences in effectiveness among individual patients treated at for hypertension with bedtime administration of amlodipine versus lisinopril. There will be an analysis of whether one medication was more effective than another and whether specific patient factors could predict who responded better to which one.

Inclusion Criteria:

• Age 40 to 80
• Newly diagnosed hypertension based on 24 hour ambulatory blood pressure monitor criteria.
• Minimum Asleep SBP mean of ≥ 120mmHg for inclusion.

Exclusion Criteria:

• Current antihypertensive medication use
• Baseline GFR < 45
• Preexisting macroproteinuria
• Chronic congestive heart failure
• History of CVA
• Diabetes Mellitus
• Pregnancy
• Night-shift work
• Other preexisting contraindication to amlodipine or lisinopril