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Fluid expansion during cardiocirculatory insufficiency was helped by cardiac output monitoring. However, the goal of fluid expansion was to increase the oxygen delivery, which consider cardiac output, but also Haemoglobin which decrease during a fluid challenge. The maximalization of cardiac output could decrease the oxygen delivery if the haemodilution was too wide. The aim of this study was to describe the oxygen delivery during a fluid expansion conducted for cardiac output maximalization, following actual guidelines.
One group of 20 anticipated patients
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hypovolemia | Fluid expansion |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| hydroxyethylstarch 130/0.4 | Drug | Bolus of 100ml of HES 130/0.4 repeated until maximization of cardiac output |
|
| Measure | Description | Time Frame |
|---|---|---|
| Measurement of oxygen delivery | Retrospective calculation of oxygen delivery (ml.min.m-2)during a fractional fluid expansion every 100ml of hydroxyethyl starch until cardiac output maximalization with oesophageal Doppler and arterial gazes (for PaO2 and Haemoglobin)from arterial line. | only during the fluid challenge |
| Measure | Description | Time Frame |
|---|---|---|
| Study of central venous saturation | Central venous gazes after each mini fluid challenge until cardiac output maximalization, from a central line | only during the fluid challenge |
| Measure | Description | Time Frame |
|---|---|---|
| study of cerebral and muscular oxygenation measured with near-infrared spectroscopy | study of cerebral and muscular oxygenation measured with near-infrared spectroscopy after each mini fluid challenge until cardiac output maximalization, from a central line | only during the fluid challenge |
Inclusion Criteria:
Exclusion Criteria:
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Mechanically ventilated patients after elective cardiac surgery with oesophageal Doppler for cardiac output monitoring and arterial and venous central line
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital of Caen | Caen | 14000 | France |
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| ID | Term |
|---|---|
| D020896 | Hypovolemia |
| D002303 | Cardiac Output, Low |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| D012816 | Signs and Symptoms |