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The purpose of this study is to investigate the role of the ratio of omega-6 to omega-3 fatty acids on executive functions. The investigators hypothesize that participants ages 7-9 years with a ratio closer to 4:1 will do better on tests of executive function than participants with a ratio closer to the purported Western diet norm of 15:1.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 7-9 year olds | Typically developing 7- to 9-year-olds will be enrolled and tested. |
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| Measure | Description | Time Frame |
|---|---|---|
| Relation between executive function and n-6/n-3 fatty acid intake | Executive function will be measured using a validated and standardized system known as CANTAB (Cambridge Neuropsychological Test Automated Battery) and correlated with the ratio of fatty acid intake. 24-hour diet recalls will be completed using the NDSR (Nutrient Data System for Research) software. Across one week, the children will be interviewed 3 times (two weekdays, one weekend day) about what they ate in the previous 24 hours. The dietary data will be averaged to arrive at the n-6/n-3 intake. The children will then come to lab for one visit where they will be assessed using the CANTAB. | up to 10 days |
| Measure | Description | Time Frame |
|---|---|---|
| Temperament | Temperament will be measured using a Rothbart written assessment completed by the caregiver. | Baseline |
| Socioeconomic status | Demographic information will be collected from caregiver using a lab-typical questionnaire. |
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Inclusion Criteria:
Exclusion Criteria:
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7-9 year olds
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| Name | Affiliation | Role |
|---|---|---|
| Carol L Cheatham, PhD | UNC-Chapel Hill | Principal Investigator |
| Kelly W Sheppard, BS | UNC-Chapel Hill | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UNC at Chapel Hill Nutrition Research Institute | Kannapolis | North Carolina | 28081 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29523147 | Derived | Sheppard KW, Cheatham CL. Omega-6/omega-3 fatty acid intake of children and older adults in the U.S.: dietary intake in comparison to current dietary recommendations and the Healthy Eating Index. Lipids Health Dis. 2018 Mar 9;17(1):43. doi: 10.1186/s12944-018-0693-9. | |
| 23824723 | Derived | Sheppard KW, Cheatham CL. Omega-6 to omega-3 fatty acid ratio and higher-order cognitive functions in 7- to 9-y-olds: a cross-sectional study. Am J Clin Nutr. 2013 Sep;98(3):659-67. doi: 10.3945/ajcn.113.058719. Epub 2013 Jul 3. |
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No biospecimens will be collected.
| Baseline |