Nutritional Failure in Infants With Single Ventricle Congenital Heart Disease

Nutritional Failure in Infants With Single Ventricle Congenital Heart Disease

The purpose of this study is to understand the causes of growth failure and to define biochemical markers of nutritional failure in patients with single ventricle Congenital Heart Disease (CHD).

Inclusion Criteria:

• CHD infants: Infants with a single ventricle CHD admitted to CCHMC for neonatal medical management or surgical palliation
• Normal controls: Healthy newborns (full-term infants with no known medical problems) recruited from CCHMC and private practices.

Exclusion Criteria:

• CHD infants: 1) Premature birth (<36 weeks), 2) Chromosomal abnormalities, 3) Major gastrointestinal, pulmonary or neurologic anomalies
• Normal controls: 1) Premature birth (<36 weeks), 2) Chromosomal abnormalities, 3) Major gastrointestinal, pulmonary or neurologic anomalies., 4) Cardiovascular anomalies