Ectopic Lipid Deposition and Insulin Resistance in After Treatment of Acromegaly

Ectopic Lipid Deposition and Insulin Resistance in After Treatment of Acromegaly

This study investigates fat distribution in people with acromegaly. The investigator is also investigating the change of fat distribution before and after treatment of acromegaly. The investigator will compare the results of people with acromegaly to the results of healthy volunteers.

Inclusion Criteria:

• Ages 18 - 75 yr (both groups)
• Study subjects with active acromegaly
• Healthy controls

Exclusion Criteria:

• Serum creatinine or alanine aminotransferase (ALT) > 2 times the upper limit of normal, metastatic cancer.
• Controls will be receiving no medications and have no chronic diseases, including cancer, hypertension or diabetes mellitus.
• Contraindications to MRI imaging (both groups) like those with certain metal implants, surgical clips or pacemakers.
• Pregnant women